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مولانا سید ابوالحسن علی ندوی

مولانا سیدابوالحسن علی ندوی
داعی الیٰ اﷲ کی وفات
افسوس اور سخت افسوس ہے کہ محفلِ دوشیں کا وہ چراغ سحر جو پچھلے برس ہی سے ضعف و مرض کے جھونکوں سے بجھ بجھ کر سنبھل جاتا تھا بالآخر ہمیشہ کے لیے بجھ گیا۔ یعنی اس دور کے بہت مقبول و مقدس بزرگ، دنیائے اسلام کے محبوب و محترم عالم، عرب و عجم کی سرمایہ افتخار و نازش ذات، شرق و غرب کی موقر و مکرم ہستی، ہر فرقہ و مذہب کے معزز و معتمد شخص، انسانیت کے پیام رساں اور علمبردار، مسلمانوں کے راہبر و رہنما، دین و مذہب کے عاشق و شیدائی، اسلام کے داعی و نقیب، ایمان و یقین کے حامل و مبلغ، عزیمت و جہاد کے پیکر، خانہ کعبہ کے کلید بردار، ہندوستان میں سرمایہ ملت کے نگہبان، ندوۃ العلماء کے ناظم، دارالمصنفین کے روح رواں، مسلم پرسنل لابورڈ اور دینی تعلیمی کونسل کے صدر، رابطہ عالمِ اسلامی اور مدینہ یونیورسٹی کے تاسیسی رکن، رابطہ ادب اسلامی کے بانی و صدر اسلامی سینٹر آکسفورڈ یونیورسٹی کے چیرمین اور ہندو بیرونِ ہند کے مختلف اداروں اور انجمنوں کے سربراہوں اور سرپرست حضرت مولانا سیدابوالحسن علی ندوی نے ۲۲؍ رمضان المبارک ۱۴۲۰؁ھ، ۳۱؍ دسمبر ۱۹۹۹؁ء کو اس سرائے فانی کو الوداع کہا، انا ﷲ وانا الیہ راجعون، اور اپنے لاکھوں عقیدت مندوں، قدردانوں، رفیقوں اور عزیزوں کو غم زدہ اور سوگوار چھوڑ کر زبان حال سے یہ کہتے ہوئے موت کی آغوش میں چلے گئے۔
اضا عونی وای فتی اضا عوا
لیوم کریھۃ و سدا و ثغر
بیسویں صدی کے اختتام سے ایک برس پہلے جب شمسی سال کے ختم ہونے میں ایک دن رہ گیا تھا تو یہ المناک اور دل دوز خبر بجلی بن کر گری۔
نعی الرکب اوفی حین آیت رکا بھم
لعمری لقد جاؤ ابشر فاوجعوا
نعواباسق الا فعال لایخلفونہ
تکاد...

Socio-Economic Factors of Differences in Public Health-Related Variables among Women: A Cross-Sectional Study

This study examines the association of living areas (slum and non-slum) with the selected public health-related variables in the presence of socioeconomic variables among married women and also having a child. A total of 150 women aged 18 to 49 are selected of which 50 women from slums and 100 women are from non-slum areas of Multan by applying the cluster and random sampling techniques. The cross-tabulation method is used to find the results. The dependent variable is Body Mass Index (BMI) and it is analyzed with the socio-economic variables such as mass media index, household characteristics and education. The findings exhibit that the BMI of the women living in the slum areas is low due to a low level of education, lack of mass media access, bad household structures, and poor or ignorant area. The women of the slum area have fewer mass media access, poor status of household characteristics and less education as compared to the women living in the non-slum areas. BMI is significantly affected by area, women's education and household characteristics except for physical work, job status, mass media access and husband education. The findings of this study suggest that to provide health facilities or to reduce the gap in public health, education, mass media access and households characteristics might be considered while making any decision related to the slum and non-slum areas.

Synthesis and Characterization of Heteroleptic Copper Complexes: As Prospective Antimicrobial, Cytotoxic and Antioxidative Agents

Copper(I) halide complexes with N,Nʹ-disubstituted thioureas and triphenylphosphine have been synthesized by the reaction of halotris(triphenylphosphine)copper(I) and respective thioureas (121) at 60 °C. The newly synthesized complexes were fully characterized by various instrumental techniques like FT-IR, multinuclear (1H, 13C, 19F, 31P) NMR spectroscopy while elemental analyses were carried out using a CHNS analyzer and atomic absorption spectroscopy. Some of the copper(I)-N,Nʹ-disubstituted thiourea complexes (A3, A7, A9, A16, B1, B3, B4, B6, B13, B14, B18, B19, C1, C3, C8, C9, C10, C12, C14, and C15) were analyzed via single crystal XRD for structural elucidation. From single crystal XRD it has been identified that copper(I) adopted distorted tetrahedral geometry in coordination with sulphur (substituted thiourea), two phosphorus (triphenylphosphine) and halogen. Most of the complexes were stabilized by intramolecular hydrogen bonding. The synthesized complexes were screened for cytotoxicity (Brine shrimp), antibacterial, antifungal, antileishmanial, antioxidant and DNA binding studies. In Brine shrimp lethality assay complexes B17 and B11 were the most active with LC50 of 19.6 µg mL–1 and 20.1 µg mL–1, respectively. In case of antibacterial activities, in the chlorinated series (A), the most active complex against E. Aerogens was A15, against B. Bronchiseptaca it was A12 and against S. Typhimurium were A9 and A3 with ZOI value comparable to that of the reference commercial drug. Similarly, in the iodinated series (C), the most active complex against B. Bronchiseptaca was C13 and against S. Typhimurium it was C9 with ZOI values of 20±1.46 and 19±1.27 mm, respectively. Against A. fumagatus(Fungi) the most active complex was B14 with a ZOI value of 19.5±1.46 mm which was comparable to that of the reference value. In Leishmanicidal activity all the test samples were active against L. tropica with LC50 values in the range of 20 to 50 µg mL–1. In the assay of DPPH Free-Radical Scavenging, all the test samples were significantly active toward DPPH and the antioxidant activity of the complexes was found within the range of 54.96-62.67%. From UV-vis spectroscopy and molecular docking studies it has also been observed that copper(I) tetrahedral complexes interact strongly with the DNA via a groove binding mode. From molecular docking the highest value of Kb was found to be 1.08×105 for A12 which is attributed to the intra-strand cross linking of benzo[d]thiazol-2-yl of thiourea in the complex with DA17 and DT6 base pairs of DNA in addition to groove binding interactions.
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