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مولانا محمد یوسف بنوری

مولانا محمد یوسف بنوری/قاری محمد یعقوب
سیمینار میں مولانا محمد یوسف صاحب بنوری کی وفات حسرت آیات کی اطلاع ملی اورواپسی میں جناب قاری محمد یعقوب صاحب(کراچی)کے حادثۂ انتقال کاعلم ہوا توسخت صدمہ اورملال ہوا۔ رحمھما اﷲ رحمۃ واسعۃً۔ اکتوبر اور نومبر میں بعض ضروری علمی کاموں میں، میں اس درجہ مصروف رہا کہ برہان کی طرف بالکل توجہ نہیں کرسکا۔یہ نظرات لکھنے کے لیے بھی بڑی مشکل سے وقت نکال سکاہوں۔ آئندہ انشاء اﷲ’’وفیات‘‘کے زیر عنوان مرحوم بزرگوں کا تذکرہ ہوگا۔ [نومبر۱۹۷۷ء]

Frequency of Renal Diseases in Diabetic Patients Renal diseases in diabetic patients

Diabetic nephropathy, also known as diabetic kidney disease is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is one of the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. Protein loss in the urine due to damage to the glomeruli may become massive, and cause a low serum albumin with resulting generalized body swelling (edema) and result in the nephrotic syndrome. Objective: The aim of this study was to determine the frequency of renal disease in diabetic patients and its complications in Pakistan. Methods: A cross sectional study was conducted at Renal and Diabetic Departments of the Sir Ganga Ram Hospital, Lahore, over a period of 3 months, after obtaining the ethical approval from the The University of Lahore. A total number of 100 Diabetic patients were selected through non probability convenient sampling technique. Patients of both sexes and all age groups were included. Results: In this study 60% were male and 40% were female. About 41% diabetic patients were 1-6 month of age, 42% were 1-5 years old and 1% of 18-23 years old who had renal diseases while 9% patients were without any renal disease. Whereas the prevalence of diabetes is more in infants than others which is 35%. But there was not significant association between onset of renal diseases with the onset of diabetes mellitus with p-value 0.24. Conclusions: Results of current study showed that diabetes mellitus effecting individuals of all ages equally but there was not significant association between diabetes and renal diseases. 

Post Mastectomy Radiotherapy in Ca Breast a Comparison of Three Protocols

This trial was designed to compare three hypofractionated protocols in postmastectomy cancinoma breast in terms of local control, toxicity & work load. A total of three hundred patients suffering from ca breast stage T2-4 , N any, M0 were randomized into three arms after mastectomy. All the patients were treated with four fields on Co60 i.e. two tangential portals for chest wall, one anterior supraclavicular & axillary field & a posterior axillary boost and were randomized into three arms i.e. 2700 CGy in 5 fractions (one week) arm A, 3500 CGy in 10 fractions (2 weeks) arm B and 4000 CGy in 15 fractions (3 weeks) arm C. Skin, cardiac, pulmonary and hematological toxicities & lymphedema were compared in addition to local control and work load. The locoregional relapses were 11%, 12% and 10% in arms A, B & C respectively. 26%, 24% & 28% patients developed metastatic disease and 17%, 18% & 20% died in the three arms. G3 & G4 skin toxicities were 37%, 28% & 14%. G2 and G3 lymphedema was 21%, 22% & 27%. Cardiac toxicity was 5%, 6% & 5% while pulmonary toxicity was 4%, 5% & 5% respectively. All the differences except skin toxicity were statistically insignificant. There were no cases of hematological depression or rib fractures. All the three short protocols were equally effective in locoregional disease control and toxicity was also comparable. They were helpful in reducing the work load and can be safely recommended for routine clinical use.
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