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نسل در نسل دشمنی

جائیداد کا تنازعہ نسل درنسل دشمنی

                 ناول نگار نے کہانی میں تین بھائیوں کا ذکر کیا ہے جو کہ ضلع خانیوال کے گاؤں ٹبہ والی میں رہتے تھے۔صادق بخش،الٰہ بخش،احمد بخش تینوں بھائیوں کے پاس زمین جائیداد بتائی گئی ہے احمد بخش جو کہ ان سب سے بڑا ہے اس کا ایک بیٹا ہے۔طلال احمد،دوسرے بھائی کی ایک بیٹی ہے بیٹی کی پیدائش پر بیوی کا انتقال ہو گیا اور تیسرے بھائی کی دو بیویاں ہیں مگر اولاد کوئی نہیں۔ان تینوں بھائیوں کا باپ جنگ عظیم دوم میں انگریزوں کے خلاف جنگ کرتا ہوا اپنے ایک بازو سے ہاتھ دھو بیٹھا اس صورت میں اسے حکومت کی طرف سے زمین الاٹ کی گئی، کچھ بعد میں یہ بھائی اپنے دماغ سے اضافہ کرتے گئے۔تینوں بظاہر بہت اچھے بھائی تھے۔ مگر طلال احمد جو کہ دل میں بغض رکھتا تھا، وہ اور اس کا باپ احمد بخش تین ہزار ایکڑ کے امورخود سے ہی دیکھتے تھے۔سب کام بہت خوش اسلوبی سے ہورہے تھے۔تینوں بھائیوں میں بگاڑ تب پیدا ہواجب دوسرا بھائی اپنی زندگی میں ہی اپنے حصے کی زمین اپنی بیویوں کے نام کردینا چاہتا تھا۔ناطق نے بھائیوں کے پیار میں بھی بتایا ہے کہ خون کے رشتے ،سگے بھائی بھی کس طرح جائیداد کے لالچ میں ایک دوسرے کے خون کے پیاسے ہو جاتے ہیں۔صادق بخش ہمیشہ سے چاہتا تھا اور اس سلسلے میں اپنے بڑے بھائی احمد بخش کو بہت بار کہہ چکاتھاکہ وہ اپنا حصہ اپنی بیویوں کے نام کرنا چاہتا ہے اور احمد بخش ہمیشہ ٹال مٹول سے کام لیتا تھا۔دونوں میں بہت تکرار ہوگئی اور بات طے پائی کہ وہ اس سال  کپاس کی کاشت پر رقم دونوں بیویوں میں تقسیم کردے گا۔اس تکرار کی وجہ سے اب بھائی ساتھ میں کم بیٹھتے تھے۔مگر احمد بخش نے اپنا...

انسانی صحت کے متعلق سائنسی ا ثبات احادیث نبویہﷺ کی روشنی میں تجزیاتی مطالعہ

The preachings of the Prophet (P.B.U.H) are equally beneficial for both  believers  and non-believers. While Muslims have reaped many benefits from prophetic teachings, those who do not believe in the Holy Prophet (saw) are also inclined to study his teachings and conclude that the scientific  principles we are  formulating now, were revealed by the Prophet  (P.B.U.H) many centuries ago. Whether it be the secrets of hygiene, medicine  and treatment, or matters of implicit principles of creation, Prophet Muhammad (P.B.U.H)'s teachings contain golden principles that encompass   the secrets of success in all matters ranging from the survival of human health to the matters of creation. The purpose of this article is to explain the sayings of the holy prophet*( P.B.U.H) which lead to scientific proofs and indicate that it is the teachings of the Prophet (P.B.U.H), from which today’s intellectuals deduce principles. But the Prophet ( PBUH) many years ago, made those golden principles clear  through his edicts and rulings in the time of technology scarcity.

Bridging Mutational and Genomic Approaches for the Development of Novel Wheat Germplasm

In the present study, chemical mutagenesis was used to induce mutations in the wheat variety NN-Gandum-1 while gamma rays (γ rays) were used to induce mutations in Punjab-11 (Pb-11). The aim of mutagenesis was to improve resistance to the disease as well as to study function of genes conferring resistance to the disease. A total of 3,634 M5 mutant lines of NN-1 and 3,600 M5 mutant lines of Pb-11, 3,533 M6 lines mutant of NN-1 and 3,483 M6 mutant lines of Pb-11 and 3,502 M7 mutant lines of NN1 and 3,453 M7 mutant lines of Pb-11 were produced and characterized for days to heading (DH), plant height (PH), spike length (SL), tillers per plant (TPP), and resistance to leaf rust (LR) and yellow rust (YR). Across all the measured traits of three mutant generations, ranges of phenotypic values among the mutant lines were significantly larger than the corresponding values of wild type of both populations (0.57–12.52 for NN-1 and 0.62–11.5 standard deviations for Pb-11). Significant correlations of the traits between mutant generations confirmed the genetic basis for these traits. A subset of 239 M7 lines (17 NN-1, 222 Pb-11) were selected for their resistance to LR and YR. These lines also showed phenotypic variations for PH (12 NN-1, 137 Pb-11), DTH (9 NN-1, 14 Pb-11), TPP (6 NN-1, 52 Pb-11) and SL (12 NN-1, 81 Pb-11). For all these traits, mutant lines showed significant improvements as compared to the corresponding wild type. Cumulatively, Pb-11 mutant population exhibited more mutants (26.18%) than the EMS-treated NN-1 population (22.76%), owing to various genetic backgrounds, type of mutagen used and environmental conditions. In the M4 generation, a total of 11 M4 lines (nine absolute resistant and two highly susceptible) and one wild type were selected for NGS-based exome capture assay. A total of 104,779 SNPs were identified that were randomly distributed throughout the wheat sub genomes (A, B and D). Induced mutations in intronic sequences predominated. The highest total number of SNPs detected in this assay were mapped to chr.2B (14,273 SNPs), which contains the highest number of targeted base pairs in the assay. The average mutation density across all regions interrogated was estimated to be one mutation per 20.91 Mb. The highest mutation frequency was found in chr.2D (1/11.7 kb) and the lowest in chr.7D (1/353.4 kb). Out of the detected mutations, 101 SNPs were filtered using analysis criteria aimed to enrich for mutations that may affect gene function. Out of these, one putative SNP detected in xv Lr21 were selected for further analysis. The SNP identified in chimeric allele (Lr21) of a resistant mutant (N1-252) was located in a NBS domain of chr.1BS at 3.4 Mb position. These lines were again screened for resistant to the rust diseases along with their yield response at multiple locations for three consecutive crop years (2014-2016). In these trials, PGMB-15-30 was found the most resistant among all the mutants and showed higher grain yield potential compared to the wild type NN-Gandum-1, Morocco and local variety Galaxy13. In the national wheat disease screening nursery (NWDSN) trials, PGMB-15-30 demonstrated high resistance to LR and YR in three provinces of Pakistan during 2015-2016. Through computational analysis, it was demonstrated that the identified SNP causes a substitution of glutamic acid with alanine, resulting in a predicted altered protein structure. This mutation, therefore, is a candidate for contributing towards resistance phenotype in the mutant line. The newly developed wheat mutant resources can contribute novel alleles which can be used in developing new wheat cultivars as well as in getting insights into various biological circuits of different complex traits in wheat.
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