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نواب سر مزمل اﷲ خاں بہادر

نواب سر مزمل اﷲ خاں بہادر
حاتم یو پی کی وفات
ہمارے صوبہ کے حاتم نواب سر مزمل اﷲ خاں بہادر نے ستمبر کی آخری تاریکوں میں اپنے وطن بھیکم پور ضلع علی گڑھ میں وفات پائی، مرحوم کئی سال سے لگاتار بیمار تھے، بخار اور کھانسی کی تکلیف تھی، ضعف کبھی بڑھ جاتا کبھی گھٹ جاتا، اور آخر اتنا بڑھا کہ پھر نہ گھٹا، چوہتر (۷۴) برس کی عمر میں دنیا کے ہر اُتار چڑھاؤ کو دیکھ کر اور ہر سرد و گرم کو آزما کر دین و دنیا دونوں کی نعمتوں سے بہرہ اندوز ہو کر ۲۸؍ ستمبر ۱۹۳۸؁ء کو اس ہری بھری دنیا کو الوداع کہا۔
مرحوم شروانی خاندان کے چشم و چراغ تھے، اور جیسا کہ وہ فرمایا کرتے تھے، سرسیدؔ کی گودوں میں کھیل کر جوان ہوئے تھے، عربی و فارسی کی تعلیم پائی تھی، اور انگریزی اتنی جانتے تھے کہ اخبار پڑھ اور گفتگو سمجھ لیتے تھے، فارسی کے شاعر تھے، مرزا سنجر طہرانی سے اصلاحیں لی تھیں، فارسی کا پورا دیوان مرتب تھا، ان کی غزلیں اور نظمیں کئی دفعہ ان کی زبان سے سنیں اور شاید ایک دو دفعہ معارف میں بھی چھپیں، تقریر شگفتہ اور پر مذاق کرتے تھے۔
مولانا شبلی مرحوم کے دوستوں میں تھے، اسی کا اثر یہ تھا کہ وہ مولانا کے کاموں اور تحریکوں سے دلچسپی رکھتے تھے، ندوہ کی طرف ان کا التفات مولانا ہی کے دم قدم اور قلم کے اشاروں سے ہوا، اور دارلمصنفین کی طرف ان کی چشم کرم بھی اسی نسبت کی مرہون ہے، دارالمصنفین اپنی چوبیس برس کی عمر میں حیدرآباد و بھوپال کی سرکاروں کے علاوہ اگر کسی محسن کے فیض سے مستفید ہوا ہے تو وہ بھیکم پور کے رئیس کی ذات تھی، مرحوم نے دارالمصنفین کی مسجد پانچ ہزار کے خرچ سے بنوائی، اور اس...

منھج القرآن الكريم في تربية الشباب المسلم

In the present age, youth occupy an important position and can play a very important role in reforming and improving the world conditions. In Quran several methods are suggested for character building of youth for example following “Uswa-e-Hasna” and by preaching and motivation of youth the fear Allah, the crated in their heard for reforming them. In some cases, the punishment can also reformed of youth. Youth is an important entity of any human society. Particularly in an Islamic society, youth has great significance. Youth is considered as a junction of past, present and future. The role of young generation cannot be neglected in the building of character, changes in circumstances and development of society. Youth should play a positive and effective role against various evils, which are prevalent in human society. What can be the religious social, political, ethical and educational duties of the Muslim? How can they play their role in reformation of society? How can they be bright stars of their country by fulfilling their duties? How can the whole humanity and particularly Islamic Ummah get benefits from their youth? The answers to these questions are central idea and theme of this article, generally in the light of Islam and particularly in the light of seerah-un-nabwiyia. In following lines, it has been tried to impart feelings of high self-esteem in the young generation who have forgotten it. It is an effort to motivate the youth for practical actions.

Comparison of Xpert Mtb/Rif With Histology for the Detection of Mycobacterium Tuberculosis in Formalin Fixed Paraffin Embedded Tissues at Aga Khan University Hospital, Nairobi

Background: Diagnosis of extrapulmonary tuberculosis (EPTB) continues to be a challenge due to the complexity of the causative organism and the wide array of pathologic features seen in this infection. A number of studies have shown polymerase chain reaction (PCR) for EPTB to be a feasible, sensitive and specific test for diagnosis of tuberculosis (TB) of which, the World Health Organisation (WHO) has given recommendations. As pertains EPTB, Xpert MTB/RIF may be used in place of conventional tests such as microscopy, histopathology and culture in lymph nodes and other tissues from patients suspected to have EPTB. It has been demonstrated that Xpert MTB/RIF can be used for fresh or frozen tissues specimens with good results. However, the use of formalin fixed paraffin embedded (FFPE) tissues, a widely available and rich source of clinical material, on the Xpert platform is yet to be described. Objectives: The aim of this study was to demonstrate the potential utility of Xpert MTB/RIF in the detection of Mycobacterium tuberculosis from FFPE tissues with histological features suggestive of tuberculosis. We compared Xpert MTB/RIF to histology for the detection of Mycobacterium tuberculosis from FFPE tissues. In those cases with a positive Xpert result, we determined the prevalence of rifampicin resistance in EPTB. Methods: Eighty randomly selected archived FFPE tissues exhibiting histological features suggestive of TB (necrotizing granulomatous inflammation, non-necrotizing granulomatous inflammation, chronic inflammation, necrotizing inflammation and suppurative inflammation) from January 1, though December 31, 2014 were retrieved. All the cases were subjected to microscopic evaluation of Haematoxylin and Eosin (H&E) stained and Ziehl-Neelsen (ZN) slides. With prior deparaffinization and lysis, all cases were also subjected to the Xpert MTB/RIF assay. Only 79 cases were included in the final analysis. This was after exclusion of one case due to an error in the Xpert MTB/RIF assay. The outcome measures were proportions of positively identified cases by each test. The data were analysed using chi - square test. Results: Xpert MTB/RIF assay detected 32.9% more cases than microscopy (53.2% versus 20.3%) which was statistically significant, (p= 0.002). None of the cases tested positive for rifampicin resistance. Seven cases however, had an indeterminate rifampicin resistance result. Conclusion: With prior deparaffinization and lysis, FFPE tissues can also be subjected to the Xpert MTB/RIF assay. A validation study to determine the clinical utility of this assay for FFPE tissues is recommended.
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Asian Research Index Whatsapp Chanel

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