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سائنس آئی بہاریں لائی

سائنس آئی بہار یں لائی
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز اسا تذہ کرام اور میرے ہم مکتب ساتھیو! آج مجھے جس موضوع پر لب کشائی کا موقع فراہم کیا گیا ہے وہ ہے:’’سائنس آئی بہاریں لائی ‘‘
صدرِذی وقار!
اللہ تعالیٰ نے انسان کو اشرف المخلوقات بنایا عظمت کا تاج اس کے سر پر سجایا اور جملہ مخلوقات میں اسے اعلیٰ وارفع مقام پر فائز فرمایا۔ اس کی عظمت کا سبب علم کے ساتھ ساتھ عقل کو بھی قرار دیا اور غیر ذوی العقول مخلوقات میں سے اس ذوی العقول مخلوقات کی اہمیت کا لوہانوری اور غیر مرئی مخلوق ملائیکہ سے بھی منوایا یہاں تک کہ وہ اس حیوانِ ناطق کے سامنے سجدہ ریز ہوئے۔
صاحبِ صدر!
یہ ساری عظمتیں ، یہ ساری رفعتیں، یہ ساری شفقتیں، یہ ساری عنایتیں ، یہ ساری سعادتیں ، یہ ساری فضیلتیں اللہ تعالیٰ نے انسان کو عطا فرمائیں کیونکہ علمِ الٰہی میں موجودتھا کہ میری کائنات کے گلشن میں بہار انسان لائے گا۔ میری زمین پر فلک بوس پہاڑوں سے جوئے شیر انسان نکالے گا، آسمان پر پرواز یہ انسان کرے گا۔ خونخوار درندوں کو مطیع میرا یہ انسان کرے گا۔ انسان کی عظمت و رفعت کی بلندیوں پر فائز کرنے والی اللہ تعالیٰ کی ذات ہے اُس نے دنیاو مافیہا کی ہر چیز انسان کے لیے پیدا فرمائی اور انسان کو اپنی عبادت کے لیے پیدافرمایا۔
جانور پیدا کیے تیری وفا کے واسطے
چاند سورج اور ستارے ہیں ضیاء کے واسطے
کھیتیاں سر سبز ہیں تیری غذا کے واسطے
سب جہاں تیرے لیے اور تو خدا کے واسطے
معزز سامعین!
سائنس علم کا ایک شعبہ ہے، سائنس کا لفظ جب قوت ِسماعت پر دستک دیتا ہے۔ سائنس کا لفظ جب قوت بصارت کو متحرک کرتا...

The Effect of Counseling and Training on Public Knowledge About Making Handsanitizer from Betel Extract

Hand sanitizers may help increase hand hygiene compliance as the results of invailability of basic needs for cleaning such as soap or water. Since alcohol has an irritating effect on the skin and burns quickly, it is currently discouraged as an active ingredient. Knowledge of covid 19 is critical for the world to have in order for individuals to be able to make informed choices on how to split the covid 19 transmission chain. This thesis employs a pre-experimental method that employs the One Group Pretest-Posttest Design approach. The paired t test was used to examine the relationship between the two variables, namely the betel leaf extract handsanitizer output preparation and the respondent's knowledge of the handsanitizer making process. Extension has an impact on increasing respondents' awareness of how to make natural hand sanitizers. The paired t-test findings indicate that the Sig. = 0.000 0.05, indicating that there is a discrepancy between the pretest and posttest. With a mean value of -5.967, this data indicates the average discrepancy between the pretest and posttest, with a range of -5.383 to -6.551 (95 percent CI), indicating that there is a difference between the pretest and posttest mean values, indicating that the pretest value has an influence on the post test. To stop the spread of Covid19, health care providers and the society must work together.

Polymorphisms of Interleukin 13 Il13 in Local Asthmatic Population

Asthma is a chronic inflammatory disorder characterized by wheezing, breathlessness, chest tightness and cough. The inflammation is responsible for bronchial hyperresponsiveness which renders the patient susceptible to certain environmental stimuli. The environmental factors alone are not responsible for these changes as they have an intricate interaction with genetic factors. In this study we determined the spectrum of symptoms and their correlation with serum IgE levels in asthmatic patients since no such data could be found for indigenous population. Cortisol and ACTH levels were determined to ascertain the status of hypothalamic pituitary adrenal axis. Interleukin 13 gene polymorphisms and their association with asthma and serum IgE levels were investigated. For the present study a detailed history was taken and peak expiratory flow measured on 164 asthmatic and 50 controls. Seventy five randomly selected patients underwent serology and SNP genotyping. Serum was analyzed for total IgE, cortisol and ACTH levels. Six SNPs of interleukin 13 gene were studied by PCR-RFLP. Four polymorphisms were from the promoter region C-1512A, T-1112C, A-646G and C-469T, one nonsynonymous polymorphism from the exon 4 A2044 G (Arg to Gln) and a 3’UTR polymorphism A2525G. The results of this research revealed that majority of patients belonged to moderate intermittent to severe persistent group. Exposure to dust was the most common triggering factor in our population. Serum IgE levels were directly proportional to the severity of asthma and were significantly correlated with history of allergy. However, no correlation was found between IgE levels and family history of asthma. Adrenal functions were © Dr Afia Hasnain 2008 xviiPhD Thesis Dr Afia Hasnain normal when compared with the control group. Two SNPs T-1112C and A2044G showed strong association with serum IgE levels and both the presence and the severity of asthma. C-1512A showed association with asthma and its severity and was the only polymorphism that showed an association with the family history of asthma. While A2525G had a weak association with serum IgE levels only. The other two polymorphisms were in very low frequency in our population and hence no association with phenotypes could be ascertained. It could be concluded from the present investigation that exposure to dust could be the most common precipitating factor of asthma in our population. The two previously studied SNPs T-1112C and A2044G are strongly associated with serum IgE levels and both presence and severity of asthma in our population sample.
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