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بہت رلاتا ہے

بہت رُلاتا ہے
گلابی رت میں!
فرشتوں کے ساتھ پرندے بھی چلے آتے ہیں
ستاروں سے ناہید،مندروں سے درگاہ۔۔۔!
خوشبو سے خمار ،تبسم سے فسوں نکل آتے ہیں
عہد شباب اور مفاہیم حکمت کے بیچ!
وفا ئیل ؑ، سرائیل ؑاور شمکائیلؑ۔۔۔!
شبنم سے وضو کرتے ہوئے۔۔۔طاق چاندنی راتوں کی قسم کھاتے ہیں
درد ائیل کے رو برو۔۔۔!
سرخ سبز عشق کا نقیب۔۔۔!
توراتِ فسوں والانجیل کا حافظ۔۔۔!
ارغوانی لہجے میں اصحاب جمال کی آیتیں پڑھتے ہوئے!
شہر عشق میں بجتی دف کے ساتھ !
مندروں میں رقص کرتی داسیاں دکھاتے ہوئے!
قم، رے اور سامرہ کی داستاں سناتا ہے۔۔۔بہت رُلاتا ہے

 

جن حویلیوں میں۔۔۔!
چاندنی درود سلام پڑھتے ہوئے۔۔۔دالانوں تک چلی آتی ہے
بہار میں سوسن و نسترن۔۔۔گلاب کیساتھ کھیلتے ہوئے!
وارثِ اسرار کا صحیفہ پڑھتے ہوئے!
سطوط اقرار و جمالیات کا قصہ سناتی ہیں
انہی حویلیوں میں !
دلفریب دھڑکنوں کے مرسلیں کا چراغ روشن کرتے ہوئے!
سرخ سبز عشق کا نقیب۔۔۔!
توراتِ فسوں والانجیل کا حافظ۔۔۔!
عذرا، ماریہ، فاریہ کا صحیفہ ہجر سناتا ہے۔۔۔بہت رلاتا ہے

انگلی کی پرکار سے۔۔۔!
فلک کی جالیوں سے لگ کر رونے والی تک!
تورات فسوں والانجیل کا حافظ۔۔۔!
سرخ سبز عشق کا نقیب۔۔۔!
محبتوں، چاہتوں کا دائرہ کھینچتا ہے
پھر بزم جمال کی دلفریب دھڑکنوں کے ساتھ تفسیر کرتے ہوئے!
شاہ بلوط کے سائے میں۔۔۔چنار وصنوبرکی سبز شاخیں لاتے ہوئے!
گزری بہار کی پوٹلی کھول کر!
سوکھی زعفرانی پتیاں دکھاتا ہے۔۔۔بہت رُلاتا ہے

وہ جب بھی تنہائی کی وادیوں میں!
یادوں کو جھنجھوڑتے ہوئے۔۔۔جنوں کو بوتے ہوئے!
حسن گلاب کے سینے میں!
شبنمی چاندنی کے خوابوں کا طلسم بن کے سماتا ہے
پھر توراتِ فسوں والانجیل کا حافظ بن کر!
ایلاف وفا کی قسمیں کھاتے ہوئے!
آوران کے محلے سے نکل کر!
حلب کی گلیوں۔۔۔دمشق کے بازاروں میں چلا آتا ہے
وہ آہو...

Higher Education for Women in Peshawar: Barriers and Issues

Higher education for women is one of the major issues in Pakistan especially in Peshawar, Khyber Pakhtunkhwa. Most of the girls quit their education at higher secondary or intermediate level, which is a negative sign both for productivity and financial system of our society. Higher education not only increases critical and rational thinking, general knowledge, ways of living, financial status of a family but also common sense. The need of higher education is more for women as they are responsible for the bringing-up of a family; unfortunately, the ratio of the higher education among women in Peshawar is decreasing, which is the point of discussion in this study. This research made an attempt to consider the possible reasons behind the issues related to the women’s higher education in Peshawar. Data was collected through Questionnaire and further analyzed by employing ANOVA. The results revealed that there are different social and cultural issues due to which higher education of women in Peshawar is not promoted; however, the increase in the enrolment of the female students has witnessed an increase. Government may make extra efforts to promote the education of women as it directly affects families in particular and societies in general.

Evaluation of the Anti-Kidney Stone Anti-Urolithiasis Activity of Natural Products, and Study of Their Mechanism of Action

The key objective of the present project was to study the preventive and curative effects of some natural products in a rat model of kidney stone disease. The first part of this thesis includes results of in vitro studies in which Boerhavia diffusa (Linn.) and Bryophyllum pinnatum (Lam.) exhibited anti-kidney stone activity by inhibiting the crystallization of calcium oxalate monohydrate crystals. A well known natural product, caffeic acid (1), was also evaluated for its in vitro antiurolithic activity, which showed a protective effect against the formation of calcium oxalate monohydrate crystals. Compound I has been obtained from various medicinal plants, including B. pinnatum (Lam.). In the second part, in vivo studies showed that B. pinnatum (Lam.) is a potent antiurolithic herb in ethylene glycol-induced urolithic rats. Twenty four hours urine analysis of the preventive group showed significant effects of herbal treatment on the urinary citrate (**p < 0.01), oxalate (**p < 0.01), calcium (*p < 0.05), magnesium (***p < 0.001), urea (***p < 0.001), and creatinine (**p < 0.01) levels. The curative treatment of rats with B. pinnatum extract also significantly regulated the altered urinary levels of citrate (***p < 0.001), oxalate (**p < 0.01), calcium (***p < 0.001), magnesium (***p < 0.001), urea (***p < 0.001), and creatinine (**p < 0.01). Similarly, caffeic acid (1) significantly regulated the pathologically altered levels of citrate (*p < 0.05) and oxalate (**p < 0.01) in the urine. Histopathological studies also revealed the protective effects of Bryophyllum pinnatum (Lam.) extract, and caffeic acid (1) on renal architecture. The third part comprised molecular studies in which renal tissues of rats from different groups were processed for RNA isolation, cDNA synthesis, reverse transcriptase-polymerase chain reaction (RT-PCR), agarose gel electrophoresis, and real-time polymerase chain reaction (RT-qPCR). B. pinnatum (Lam.) extract increased the expression of prothrombin fragment 1 (*p < 0.05), bikunin (*p < 0.05), and Tamm-Horsfall genes (*p < 0.05), while it decreased the renal expression of osteopontin gene ((*p < 0.05), in comparison to the pathological control. In case of caffeic acid (1), prominent effects were observed where the expression of bikunin (*p < 0.05), prothrombin fragment 1 (*p < 0.05), and Tamm-Horsfall (**p < 0.01) increased significantly, while that of osteopontin gene (**p < 0.01) significantly decreased as compared to the pathological control. The results of western blotting also indicated that caffeic acid (1) has the potential to affect the expression of prothrombin fragment 1 at the protein level. The outcomes of this study could help to understand the possible molecular mechanism behind the antiurolithic effects of related natural products, and to investigate their therapeutic potential. A bioassay-guided isolation of secondary metabolites from these plants needs to be conducted in order to identify compounds responsible of the antiurolithic activity.
Asian Research Index Whatsapp Chanel
Asian Research Index Whatsapp Chanel

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