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حکیم الیاس کٹھوری

حکیم الیاس کٹھوری
حکیم الیاس کٹھوری مقیم میرٹھ پچھلے دنوں اچانک انتقال فرماگئے۔ مرحوم بڑے حاذق و فائق طبیب تھے۔مزاحیہ انداز میں اپنے چاہنے والوں کو ہمیشہ خوش رکھا کرتے تھے۔قاری محمدطیب اورحضرت مفتی عتیق الرحمن عثمانیؒ کے خاص شیدائی و معتقد تھے۔عالموں سے انھیں زیادہ ہی محبت تھی خلوص کے ساتھ ہمہ وقت ان کی خدمت میں جٹے رہتے ۔نیکی وشرافت کی تصویر تھے۔
ادارہ ندوۃ المصنفین دہلی کے خصوصی نمبر ’’مفکرملّت ‘‘ میں بھی حکیم الیاس صاحبؒ نے مفتی عتیق الرحمن عثمانی ؒ کے سلسلے میں بڑا ہی پراز معلوماتی مضمون برائے اشاعت ارسال فرمایاتھا ۔
ادارہ ندوۃ المصنفین دہلی حامد الانصاری غازی ،حکیم عبدالقوی دریابادی اورحکیم الیاس کٹھوری کے انتقال پرملال پراپنے گہرے رنج وغم کااظہار کرتا ہے اور اﷲ تعالیٰ سے دعاہے کہ تمام متعلقین کوان کی وفات کے صدمہ کوبرداشت کرنے کی توفیق عطا فرمائے ۔آمین۔ [نومبر ۱۹۹۲ء]

 

A Welcome Note from the Editor

We are delighted and proud to welcome you to the second issue of Volume 2. Each article received and accepted is an important contribution to the already existing knowledge in the field of Biomedical Sciences. All the editorial team is excited about the progress of PBMJ as an international journal. As editors, we would like to express our heartiest congratulation to the team and welcome to the authors and readers. We are also grateful to the advisory board and managing editors. We hope that PBMJ can promote the academic and applicable research and improve the research activities and collaborations. We are aware of the bumps along the way, but we are determined to keep pursuing the research goals to meet the high quality standards and move forward with great courage. If you have any suggestions to improve, you may write to us as a reader. In the age of technology, we can actively conversate with the readers and get their feedback to improve the quality with their valuable input. PBMJ will continue to serve the Biomedical Sciences as an outlet for high-quality research. This is an exciting time for the journal and we look forward to working with authors, the Editorial board and the team to make PBMJ as a leading source for work in the space.

Bioactivity Guided Isolation of Anticancer Compounds from Oleoresin of Boswellia and Pinus Species

Oleoresins are secondary metabolites of resinous plants, mainly composed of essential oil and resin acids. The present research work was conducted for the development of methodology for isolation of anticancer compounds from oleoresins of Boswellia and Pinus species. Conventional and advanced extraction techniques such as Hydro-distillation, steam distillation and supercritical fluid extraction (SCFE) method were used for extraction of essential oil from oleoresins. For optimum extraction yield of essential oil, hydro-distillation and steam distillation methods were performed under different temperature conditions. It was observed that essential oil yield in both plants oleoresin was increased on increasing extraction temperatures. These essential oils were further separated in to different fractions and sub fractions on the basis of their boiling points by vacuum fractional distillation method. Moreover, the biological activity of essential oils, fractions and sub fractions were performed under bioactivity guided assays. Antioxidant potential of essential oils, fractions and sub fractions was determined through different antioxidant assays. It was observed that most the essential oils, fractions and sub fractions revealed moderate level of antioxidant activity. Moreover, it was found that all the essential oils, fractions and sub fractions showed excellent antimicrobial and antitumor activity. Cytotoxicity was determined through haemolytic assay and their results expressed that all the tested essential oils, fractions and sub fractions exhibit weak cytotoxic activity. The chemical composition of essential oils was determined through GC-MS. The results showed that α-pinene, β-pinene, 3-carene and longifolene were the major chemical components of Pinus roxburghii oleoresin essential oils. Similarly, the chemical composition of Boswellia serrata oleoresin essential oils showed that α-pinene, β-pinene, pinocarveol and verbenol were the main chemical compounds and these chemical compounds might be responsible for their biological activity. Moreover, it was observed that the chemical composition of essential oils significantly vary with extraction methods.
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