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جریبِ حیات

جریب حیات(افسانہ)

ڈاکٹر مجاہد عباس ،لیکچرر، نمل یونیورسٹی اسلام آباد

جریب زمین کے لیے ہے یا حیات کے لیے،  زمین اور حیات دونوں ہی اس سے ناواقف رہتی ہیں۔ البتہ انسان جو زمین سے اگایا جاتا ہے اور پھر زمین میں ہی دبایا جاتا ہے جریبوں کی  پیمائش بن کے رہ جاتا ہے۔

اقصیٰ کےلبوں پر  سَرمیلی بسنت کے پھول کھل رہے تھے۔اُس نے  زمین کی طرف جھکتے ہوئے اپنی زلف ِ دراز کو بائیں کان  کی اوٹ میں سُلا دیا اور زمین پر گرے کاغذ کو ہتھیلی پر رکھ کر دل میں اُتار لیا۔ اُسے اپنے پیلے لباس  کی مہک  وصل  کی چاندنی رات کا قصہ ِ ناتمام سنارہی تھی مگر وہ مسلسل سوچوں کی جریب سے پرائے موریے اور بورنیو کے جنگلات کی پیمائش کر رہی تھی۔وہ اُن جنگلات کے سحر انگیز مناظر میں یوں کھوئے جا رہی تھی  جیسے دین و دنیا کی متاع ِ بے پایاں اُسے نصیب ہو گئی ہو۔وہ ایک ایک پودے کے ایک ایک پتے کے ایک ایک  ملائم اور تیزکنارے کو چھو کر  اس کی خوشبو اور لطافت کو  جذب کر رہی تھی۔ وہ  خود کو  پرسکون سبز سمندر کی کشتی  سمجھ کر ہوا کے رخ پر دھیرے دھیرے رواں دواں تھی۔ ابھی اُس نے اپنی کمر سیدھی نہیں کی تھی کہ اسےگلی سے گزرتی ہوئی لاری کی آواز سنائی دی جس پر اے کلاس چنیوٹی فرنیچر  سلیقے سے لادا گیا تھا۔

 اس  نے ٹیَلوں لگے فرش سے پلاسٹک کی میز اور کرسیاں اٹھا کر گھر کی پچھلی طرف لان میں رکھ دیں جہاں پھولوں کے احاطے میں سبزے کی بہار تھی۔  یہ لان اس کی زندگی میں افضال کی طرح  اہمیت رکھتا تھا۔ وہ جب بھی تھک جاتی تو وہاں آرام کرتی تھی، پودوں...

Socio-Economic Effects of Rampant Divorce in Nigeria: The Northern Muslims Scenario

Divorce seems to be more socially accepted nowadays and it is the most won issue in the modern world. Divorce in the family always signals dangers and insecurity in the society. Findings have indicated that divorce has negative impact on spouses as well as the development of children in the society, and it leads to number of social problems such as prostitution by young ladies. It will be difficult for a woman to cater for all the basic needs of the child single handedly. It will grow up demoralized. He suffers different types of deprivations including parental love, care and affection. Such children grow up humiliated and heartless. They resort to various crimes such as robbery, rope, arson and other related wrong doings. It is also observed that, divorce has a negative impact on man too, men cannot really make their feelings vocal. The stress involved in the divorce can cause lack of sleep, depression, fatigue and listlessness; a divorce can have numerous psychological implications as well. The methodological approach used in this paper is descriptive, prescriptive and annalistic; meanwhile the method of data collection is historical and empirical.

Phytochemical Analysis and Plant Mediated Nanoparticles Synthesis from Quercus Incana

Phytochemical Analysis and Plant Mediated Nanoparticles Synthesis from Quercus Incana Traditional medicines play significant role as healers, in addition to the synthetic drugs, for different diseases. Plants form a significant part of traditional healing and hence, Quercus incana was chosen for nanoparticles synthesis, biological screening and phytochemical analysis to determine a scientific basis for the traditional use of this plant. The phytochemical screening was carried out using column chromatography (CC) followed by thin layer chromatography (TLC), identification and structure elucidation of pure compounds were done by using spectroscopic and spectrometric techniques (1D and 2D-NMR, IR, UV, Mass). Through phytochemical analysis, fourteen compounds were isolated, among them four compounds (decane-1, 1,4-triol [1], 4-hydroxy-3-(hydroxymethyl) pentanoic acid [2], 2-(4-hydroxybutan-2-yl)-5-methoxyphenol [3], and 3-(2-hydroxy-4 methoxyphenyl) butane-1, 1-diol) [4] were new rare class of aliphatic alcohols and acids. Along these new compounds ten known compounds (Cirsimaritian [5], Eupatorin [6], b-amyrin [7], Betulin [8], Ursolic Acid [9], 3 β-hydroxy-30-Norlupan-20-one[10], 12-Oleanen-3yl acetate [11], β-Sitosteryl-D-glycoside [12], 1-Triacontanol [13], and 4-methoxy-1-methyl-2-oxo-1, 2-dihydropyridine-3-carbonitrile) [14], were isolated for the first time from Quercus incana except Ursolic Acid. Small sized, polydispersed gold nanoparticles were synthesized using all fractions of Quercus incana (n-hexane, chloroform, ethyl acetate, n-butanol, aqueous fraction) and isolated compound (b-amyrin). 4-Methoxy-1-methyl-2-oxo-1, 2-dihydropyridine-3-carbonitrile was used for the synthesis of monodispersed silver nanoparticles. Biological screening of extracts, nanoparticles and pure compounds showed tremendous results. All fractions of Quercus incana were analyzed for antioxidant activity, nitric oxide scavenging activity, total phenolic content and antimicrobial potential. Among all fractions, ethyl acetate and n-butanol fractions showed immense biological activities as these fractions may contain polyhydroxy compounds which contribute to the enhancement of activities. Synthesized nanoparticles were screened for antibacterial activity and it was found that extract xi loaded nanoparticles may be used as antibacterial agents by comparing it with crude extract. Crude extract was found inactive at low concentration whereas nanoparticles showed good activity against human pathogens. The unique properties of silver and gold nanoparticles have stimulated the increasing interest in the application of nanoparticles in interfacing biological recognition events with signal transduction and in designing biosensing devices exhibiting novel functions. The recognition behavior of nanoparticles were explored with different drugs and results showed that only Ag-NPs (4-methoxy-1-methyl-2-oxo-1, 2-dihydropyridine-3-carbonitrile) had biosensing ability towards cephalexin. Isolated compounds were screened for anti-biofilm, cytotoxic and anticancer activity. Eupatorin, Cirsimaritin and β-Sitosteryl-D-glycoside showed good anti-biofilm activity which explored the medicinal use of these compounds in pharmaceutics as an anti-biofilm agent. A preliminary screening of natural product compounds was carried out against NCI-H460 (Non-Small Cell Lung Carcinoma) cell line. The compounds; 12-Oleanen-3yl acetate, Betulin, Eupatorin, and Cirsimaritin showed good anticancer activity. The compound, 12-Oleanen-3yl acetate was found more active anticancer agent against NCI-H460 cell line. Similarly, Cirsimaritin, 12-Oleanen-3yl acetate and Betulin showed good cytotoxic activity against NIH-3t3 (Normal Fibroblast) cell line.
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