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مولوی نور عظیم ندوی

آہ! مولوی نور عظیم ندوی
دارالعلوم ندوۃ العلماء کے لائق فرزند اور ہونہار استاد مولوی نور عظیم ندوی چند ماہ کی علالت کے بعد وفات پاگئے، اِناﷲ وَ اِنا اِلَیہ رَاجِعُون۔
وہ دارالعلوم سے فراغت کے بعد مزید تعلیم کے لیے مصر گئے، اردو کی طرح عربی لکھنے اور بولنے کی اچھی مشق تھی اور درس و تدریس کے ساتھ ہی تقریر و تحریر میں بھی اپنا جوہر دکھاتے تھے، جلسوں کی نظامت بڑی خوبی اور سلیقہ سے کرتے تھے، جس سمینار کی کاروائی وہ چلاتے وہ ضرور کامیاب ہوتا۔
پڑھنے لکھنے کا اچھا ذوق تھا اور اسی میں ان کا سارا وقت گزرتا، ندوۃ العلماء سے شائع ہونے والے اردو اور عربی جرائد میں ان کے مضامین وقتاً فوقتاً چھتے تھے۔ ایک زمانہ میں ندائے ملت کے عملاً وہی اڈیٹر تھے، تعلیم اور دوسرے موضوعات پر اس کے خاص نمبر بھی نکالے، مولانا سید ابوالحسن علی ندوی مدظلہ کی سرپرستی میں رابطہ ادب اسلامی کا قیام عمل میں آیا تو اس کے روح رواں مولانا سید محمد رابع ندوی کے یہی دست راست اور رابطہ کے ترجمان کے ایڈیٹر بھی تھے۔ ان کے پاس بعض اشخاص اور اکیڈمیوں کے مسودے تبصرے یا اصلاح کے لیے آتے تھے جن کو بڑے غور و توجہ سے پڑھتے، تحریر کی خوبیوں اور خرابیوں پر ان کی نظر فوراً پڑتی۔ اس معاملہ پر مولانا علی میاں مدظلہ بھی ان پر اعتماد کرتے تھے۔
ان کا وطن ضلع بستی تھا اور وہ مسلکاً اہل حدیث تھے لیکن ندوۃ العلماء میں شیرولشکر کی طرح گھل مل گئے تھے، بڑے خاموش طبع، کم سخن، خلیق اور متواضع تھے، ان کی عمر پچاس (۵۰) کی رہی ہوگی، آئندہ ان سے بڑی توقعات وابستہ تھیں لیکن ابھی اپنی چمک دمک بھی نہیں دکھانے پائے تھے کہ وقت موعود آگیا۔
؂ خوش درخشید ولے...

EFFECTS OF MULLIGAN ROTATIONAL MOVEMENT VERSUS MEDIAL GAPPING TECHNIQUE ON PAIN, RANGE OF MOTION AND DISABILITY IN PATIENTS WITH KNEE OSTEOARTHRITIS

Background and Aim: To compare the effects of mulligan rotational movement and medial gapping technique on pain, range of motion and disability in knee osteoarthritis patients. Methodology: This study was a Randomized Clinical Trial. The data was collected using a convenience sampling technique. Data was collected from Jinnah Hospital Lahore, from 15th December – 30th June 2022.36 subjects (males and females) were recruited in two groups. The first group received Mobilization with movement along with a conservative treatment protocol. The second group received the Medial gapping technique along with conservative treatment protocol. Each group was treated for four weeks in which three sessions per week were given. Numeric pain rating scale and the disability index were used as outcome measures. Data was analyzed through statistical package for the social sciences (SPSS) version 25. Results: Within-group comparison by paired t-test showed the p-value was significant <.05, indicating that both treatment was effective in improving symptoms. Between groups, comparison by independent t-test showed that Mulligan Mobilization Technique is more effective than the medial gapping technique in improving pain disability and quality of life. Conclusion: The study concluded that Mulligan Mobilization Technique provides more clinical benefits regarding pain, disability and range of motion in osteoarthritis patients than Medial Gapping Technique.

Isolation, Structure, Elucidation and Phytotoxicity of Allelochemials from Cocks Comb Celosia Ergentea .

Laboratory experiments were conducted to screen plants i.e. Celosia argentea, Celosia cristata, Mirabilis jalapa, Mangifera indica, Moringa oleifera, Ziziphus jujuba, Ziziphus mauritiana, Delonix regia, Morus alba, Albizia procera and Albizia lebbek, for their allelopathic potency on Lepidium sativum. Maximum inhibition (97%) to root elongation was observed at 10% concentration of Celosia argentea extract; however, Mangifera indica at 10% concentration totally inhibited the germination of seeds. On the basis of results of present studies and literature survey, Celosia argentea was selected for further study. Different concentrations of Celosia argentea parts i.e. roots, stem, leaves and flowers were compared for their; (a) allelopathic potential (b) total phenolic contents and (c) individual phenolic compounds through Mass Spectrometry (MS). Based on literature survey and present studies, leaves of Celosia argentea were selected for isolation, purification and identification of herbicidal compounds using bioassay guided isolation method. Solvent extraction method using different solvents and High Performance Liquid Chromatographic (HPLC) method using different solvent systems were optimized. Finally, two types of extraction methods i.e. aqueous and methanolic extractions were used. Aqueous and methanol extracts were partitioned with n-hexane, then with ethyl acetate and the remaining extracts were divided into two parts. One part of each extract was subjected to acid hydrolysis to release the phenolic compounds from sugar moieties and then extracted with ethyl acetate, while second part was lyophilized. All the organic solvents were evaporated and residues were dissolved in methanol to prepare 4000 ppm solutions and were used for bioassay study against Lepidium sativum. The highest inhibition of seed germination (100%) was caused by acid hydrolyzed and ethyl acetate fractions followed by lyophilized fraction. Fractions with inhibitory potency i.e. ethyl acetate, acid hydrolyzed and lyophilized fractions were used for analysis through Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC) and Liquid Chromatography Mass Spectrometry (LCMS). More than 60 compounds including quercetin, quercetin 3-O-glucoside, quercetin pentose glucuronide, gallic acid, gallic acid 4- O-glucoside, m-hydroxybenzaldehyde, pholoroglucinol, phloroglucinol glucoside, mcoumaric acid, catechol etc. were identified as allelopathic agents. Most inhibitory fractions i.e. ethyl acetate and acid hydrolyzed fractions of methanolic extract were further divided into five fractions through Preparative Thin Layer Chromatography. Different concentrations of five fractions that were obtained from this separation were subjected to bioassay study against Lepidium sativum. The active fractions i.e. F2 and F5 were further separated on Preparative Thin Layer Chromatography in order to purify individual compounds. Active compounds were then analyzed with LCMS and Nuclear Magnetic Resonance (NMR). To our knowledge compounds such as 3,5-dihydroxybenzaldehyde, p-coumaric acid were first time identified as herbicidal compounds in Celosia argentea. In addition to this work, Mirabilis jalapa, Mangifera indica, Delonix regia, Morus alba and Moringa oleifera leaves were also subjected to bioassay guided isolation method and active fractions were analyzed for allelopathic compounds using HPLC and MS.
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