Search from the Journals, Articles, and Headings
Advanced Search (Beta)
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...

سیمیں کرن کے افسانوں میں سماجی و تہذیبی عکس

سیمیں کے افسانوں میں سماجی و تہذیبی عکس

انعم زاہد

بڑے ادیب کی پہچان اس کی تخلیقی انفرادیت ہوتی ہے اور یہ ہی انفرادیت اسے دوسرے ادیبوں سے تشخص عطاء کرتی ہے اس کے فن کی خوبیاں اس کے بعد آ تی ہیں بلاشبہ سیمیں کرن موجودہ دور کے ادیبوں میں ایک جانا پہچانا نام ہیں آ پ اردو ادب میں فکشن نگاری ،تبصرہ نگاری ،اور کالمز لکھنے میں پیش پیش ہیں ۔۔۔۔۔

      خالدہ حسین نے کہا تھا کہانی لکھنے کا عمل میرے لیے اپنے وجود سے رشتہ قائم رکھنے کی ایک کوشش کا نام ہے تو جب میں اپنا وجود خطرے میں محسوس کرتی ہوں تو خود کو لکھنے پر مجبور پاتی ہوں ۔۔۔۔۔! بلکل یہ ہی رشتہ سیمیں کا کہانیوں کے ساتھ ہے ان کے نزدیک ادب زندگی کے حبس اور گھٹن میں ایک تازہ ہوا کا جھونکا ہے ادب ایک ایسی کھڑکی ہے جو اندر باہر کھلتی ہے وہ کہتی ہیں کہ میں کہانی کب لکھتی ہوں وہ مجھے خود گلے آ ملتی ہے کسی سہیلی کی طرح ۔۔۔۔۔۔کسی کردار کی صورت ۔۔۔۔اور میرے کان میں سرگوشی کرتی ہے کہ مجھے پڑھو مجھے لکھو۔۔۔۔۔۔! اب تک مصنفہ کے 3 افسانوی مجموعے،  2 ناول اورمختلف سماجی و سیاسی موضوعات پر کالمز تبصرے چھپ چکے ہیں آ پ نے ہر صنف ادب میں طبع آزمائی کی ہے اور کامیاب ہوئی ہیں۔

  ادیب ،ادب ،اور سماج کا آپس میں گہرا تعلق ہوتا ہےایک ادیب بہت حساس طبیعت کا مالک ہوتا ہے معاشرے کے اندر بگاڑ پیدا کرنے والے عوامل اسے ہمیشہ بے چین رکھتے ہیں اور لکھنے پر آ مادہ کرتے ہیں سیمیں کرن بار بار سنی سنائی کہانیاں پیش نہیں کر تی ہیں ان کے ہاں نمایاں ترین موضوعات میں...

الاباحة في الشريعة الإسلامية والقانون الوضعي

Permissibility (al-Ibāḥah) is a kind of the Islamic law, which gives option to someone to do or not to do something. If something is done by someone under this order, no punishment or reward is liable. It nullifies the delinquency. This paper defines the lexical and technical meanings of permissibility as defined by different Islamic scholars like alShāṭibī, al-Āmidī and al-Ghazālī and the conventional law that how it removes responsibility of delinquency of an act and makes it permissible for person, who does it. Its different kinds and causes for permissibility have been discussed. It has general and particular kinds. It has also been differentiated from insanity: that when a person commits an offense under defective understanding such as childhood, mental illness and in sleeping. These conditions remove someone’s responsibility and one cannot be prosecuted by both the laws. Different rules regarding mistake and ignorance in the case of al-Ibāḥah (permissibility) has been discussed in detail. There are limitations of al-Ibāḥah and if the limits of alIbāḥah are transgressed, then, the act converts into criminality. The author, in this paper, presents a comparative study of the Islamic Law and Conventional Law on the issue of al-Ibāḥah.

Designing and Fabrication of Microfluidic Device for Therapeutic Drug Monitoring

Cardiovascular diseases are one of the leading causes of mortality in Pakistan with prevalence rate of 19 %. Digoxin, a cardiac glycoside with positive inotropic effect is most commonly prescribed to cardiac patients; involving therapeutic monitoring of drug in serum/plasma through lengthy immunoassay procedures in practice. Also, the detection facility is restricted to private labs in major cities of Pakistan. Nanotechnology with the help of nanomaterials as compared to conventional lengthy procedures offers robust, patient centered on chip methodologies for detection of therapeutically important drugs in serum/plasma. The aim of the current study was fabrication of microfluidic device offering on chip QDs based detection of clinical range of digoxin (0.8-2.0 ng per ml) in custom-made optical setup. To achieve the said objectives, sequence of experiments were conducted. It was imperative to delineate the effect of pH of media on the fluorescence of zinc sulphide (ZnS). ZnS nanowires were conjugated with different log dilutions of mercaptoacetic acid (MAA) and digoxin antibody (Ab). To observe the effect of each dilution on fluorescence of NWs, pH of the media was monitored before conjugation. This study highlights the enhancement in PL of ZnS NWs when pH of the media is almost equal to the pKa of carboxyl group of MAA (pH ~ pKa). While, quenching in fluorescence was observed when pKa < pH> pKa. Thus, proving our hypothesis of use of ZnS as a fluorescent tag for biological applications. The effect of pH, ions in media and time of incubation on the PL of MAA coated QDs was studied by incubating dots in three different phosphate buffers. The pH of media for each buffer was adjusted as acidic (pH <7.2), neutral (7.2 - 8.0) and basic (pH> 14.0).The PL response from dots in buffer 1 was more profound as compared to other two buffers. The current study demonstrated maximum fluorescence from dots in buffer 1 within pH range of 7.0 – 10.0, which increases with increasing time of incubation.Electrochemical analysis was performed to study the mechanism of electron transfer from QDs to linker (MAA) and then to Ab using electrochemical analysis. Electrochemical analysis shows resistance in electron transfer when electrode was modified with QDs and Ab conjugated QDs (QD-MAA-Ab) as compared to when modified with MAA only. The number of electrons calculated during the oxidation or anodic cycle were: 2, 1,3 and 4 for GCE, QD, QD-MAA and QD-Ab, respectively. During the reduction or cathodic cycle, the electrons found were 2, 1,4 and 6 for GCE, QD, QD-MAA and QD-Ab. Finally, detection of different log dilutions of digoxin inclusive of the therapeutic range (0.8-2.0 ng/ml) spiked in PBS buffer (1ml) using emission (quantum dots (QD)) and plasmon based (gold nanoparticles (SERS)) methods. Limit of detection (LOD) achievable through emission-based methodology was 0.5 ng/ml while 0.4 ng/ml through plasmon resonance of gold nanoparticles. Then the emission-based detection was performed in fabricated microfluidic device using homemade optical detection setup. The fabricated device is of ((H x W x D) 2.7’’ x 0.98” x 0.005)) as compared to conventional digoxin detection machine (Architect i2000SR: (H x W x D) 48’’ x 61” x 49”). The current study envisages replacement of conventional methodologies with microfluidic device or chip using quantum dots and SERs based tags as compared to conventional enzyme-based labels. The said device would be cost effective, portable and can easily be carried to remote areas of country.
Asian Research Index Whatsapp Chanel
Asian Research Index Whatsapp Chanel

Join our Whatsapp Channel to get regular updates.