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’’نیل کے سنگ‘‘پر ایک نظر

نیل کے سنگ ‘‘پر ایک نظر

                                                                                                                ایڈوکیٹ بشیر مراد

                                                                                                                                آزاد کشمیر

شاعری کے لیے کچھ نہیں کرنا پڑتا یہ کھڑے کھڑے ہو جاتی ہے۔ بعض اوقات تو سوئے سوئے بھی سر زد ہو جاتی ہے کہ اس کا تعلق آمد سے ہے جس کے لیے جامد ہونے کی قطعاً ضرورت نہیں۔ لیکن نثر کا معاملہ الگ ہے۔ اس کے لیے باقاعدہ اکڑوں ہو کے بیٹھنا پڑتا ہے۔ یعنی یہ وہ ریاضت ہے جو حالت رکوع میں کی جاتی ہے۔

نثری اصناف میں سفر نامہ تو اور بھی جوکھم کا کام ہے کہ اس کی طلب میں سفر بھی کرنا پڑتا ہے جو بسا اوقات انگریزی کا Suffer ثابت ہوتا ہے۔ گویا یہ ادب کی ایسی صنفِ گراں بار ہے جس کو صنفِ نازک کی طرح قابو کرنا آسان نہیں ہوتا۔ اس کے حصول کے لیے شدید مارا ماری اور بے تحاشا جتن کرنے پڑتے ہیں۔ پہلے سفر کرنے کا سلیقہ اور پھر اسے بیان کرنے کا قرینہ ہونا چاہیے۔

ہمارے دوست ڈاکٹر یوسف میر کی محبت کہ ڈاکٹر الطاف یوسف زئی کا مصری سفر نامہ ارسال کیا۔ مشاہدہ عام ہے کہ یوسف نام کے لوگ خوب صورت ہوتے ہیں۔ پھر بندہ ذات کا بھی یوسف زئی ہو اور مصر سے محبت نہ ہو یہ کیسے ممکن ہے۔ پس یہ طے ہے کہ یہ سفر نامہ سراسر فطری محبت کا شاخسانہ ہے۔ اگر یقین نہ آئے تو پڑھ کر دیکھ لیجیے۔

کچھ سفر نامے تو محض سفر کی صعوبت برادشت کرنے کی خاطر لکھے جاتے ہیں جن کے پڑھنے سے قاری کو بھی شدید تھکاوٹ ہوتی ہے۔ اس قبیل کے سفر نامے یوں شروع ہوتے ہیں۔

’’میں صبح سویرے جاگا ،...

Probing Interpersonal Dynamics: A Thematic Analysis of Kamila Shamsie's 'Best of Friends'

This research scrutinizes Kamila Shamsie's novel, “Best of Friends”, authored in September 2022, employing a qualitative methodology and data analysis approach to discern major thematic elements. The study identifies five principal themes, encompassing ambivalence within friendships, societal norms and the suppression of desires, political and ethical decision-making, the construct of womanhood, and the motif of unhomeliness. This study applies Braun and Clarke's established six-phase thematic analysis framework (2006) to achieve its research objectives. The research expounds upon the interplay of these identified themes and their reverberations within the lives of the individuals central to the narrative, illuminating the intricacies that underpin the friendship between the main characters. Significantly, the analysis establishes a poignant connection between the novel's title, 'Best of Friends,' and the central theme of ambivalent friendships explored therein. This investigation not only advances comprehension of the thematic nuances within the novel but also underscores the depth and complexity of the issues it addresses. It serves as a foundational exploration, providing a springboard for future research on this recently published work and presenting a diverse array of narrative facets for scholarly inquiry.

Comparison of Xpert Mtb/Rif With Histology for the Detection of Mycobacterium Tuberculosis in Formalin Fixed Paraffin Embedded Tissues at Aga Khan University Hospital, Nairobi

Background: Diagnosis of extrapulmonary tuberculosis (EPTB) continues to be a challenge due to the complexity of the causative organism and the wide array of pathologic features seen in this infection. A number of studies have shown polymerase chain reaction (PCR) for EPTB to be a feasible, sensitive and specific test for diagnosis of tuberculosis (TB) of which, the World Health Organisation (WHO) has given recommendations. As pertains EPTB, Xpert MTB/RIF may be used in place of conventional tests such as microscopy, histopathology and culture in lymph nodes and other tissues from patients suspected to have EPTB. It has been demonstrated that Xpert MTB/RIF can be used for fresh or frozen tissues specimens with good results. However, the use of formalin fixed paraffin embedded (FFPE) tissues, a widely available and rich source of clinical material, on the Xpert platform is yet to be described. Objectives: The aim of this study was to demonstrate the potential utility of Xpert MTB/RIF in the detection of Mycobacterium tuberculosis from FFPE tissues with histological features suggestive of tuberculosis. We compared Xpert MTB/RIF to histology for the detection of Mycobacterium tuberculosis from FFPE tissues. In those cases with a positive Xpert result, we determined the prevalence of rifampicin resistance in EPTB. Methods: Eighty randomly selected archived FFPE tissues exhibiting histological features suggestive of TB (necrotizing granulomatous inflammation, non-necrotizing granulomatous inflammation, chronic inflammation, necrotizing inflammation and suppurative inflammation) from January 1, though December 31, 2014 were retrieved. All the cases were subjected to microscopic evaluation of Haematoxylin and Eosin (H&E) stained and Ziehl-Neelsen (ZN) slides. With prior deparaffinization and lysis, all cases were also subjected to the Xpert MTB/RIF assay. Only 79 cases were included in the final analysis. This was after exclusion of one case due to an error in the Xpert MTB/RIF assay. The outcome measures were proportions of positively identified cases by each test. The data were analysed using chi - square test. Results: Xpert MTB/RIF assay detected 32.9% more cases than microscopy (53.2% versus 20.3%) which was statistically significant, (p= 0.002). None of the cases tested positive for rifampicin resistance. Seven cases however, had an indeterminate rifampicin resistance result. Conclusion: With prior deparaffinization and lysis, FFPE tissues can also be subjected to the Xpert MTB/RIF assay. A validation study to determine the clinical utility of this assay for FFPE tissues is recommended.
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