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مولانا سید سراج احمد رشیدی

حضرت مولانا سید سراج احمدرشیدی مرحوم
اس سلسلہ میں ہم کو اپنے استاذ حضرت مولانا سید سراج احمد رشیدی کابھی ماتم کرناہے۔ حضرت مولانا دیوبند کے قدیم اساتذہ میں سے تھے۔’القاسم‘ کے دور اوّل میں اس کی ادارت کے فرائض آپ سے متعلق تھے۔ صاحب علم وفضل ہونے کے ساتھ صاحب باطن تھے، حضرت مولانا گنگوہی سے نسبت حاصل تھی، بے حد ذاکر شاغل، وضع کے پابند، اخلاق ومروت کامجسمہ، بزرگانہ خصائل وشمائل کے پیکر، طلبہ کے مونس وغمخوار،دوستوں کے جاں نثار، دوست اورچھوٹوں کے مشفق وشفیق بزرگ تھے۔ دیوبند میں عرصہ دراز تک مشکوۃ شریف کاخصوصاً اور ادب وفقہ کی اعلیٰ کتابوں کاعموماً درس دیتے رہے۔۱۹۲۸ء میں حضرت الاستاذ علامہ سید محمد انورشاہ اپنی جماعت کے ساتھ دیوبند سے ڈابھیل منتقل ہوئے تو آپ بھی اس کارواں کے بزرگانِ کارواں میں سے ایک تھے، صدحیف کہ وہاں تقریباً دس سال تک علم حدیث کی خدمت جلیلہ میں منہمک رہنے کے بعد آپ نے داعیٔ اجل کولبیک کہا اور اس دنیائے دنیٰ کوہمیشہ کے لیے الوداع کہہ گئے۔ اناﷲ واناا لیہ راجعون۔
آپ کی صورت دیکھ کر بزرگانِ سلف کی یاد تازہ اورآپ کی باتیں سن کر قلب ودماغ کو خاص مسرت ہوتی تھی۔آپ عالم کامل تھے اورشاعر خوش نوا بھی۔ آپ علم حدیث وادب کے مدرس بھی تھے اورخوش بیان وبذلہ سنج بھی، سنجیدہ ظرافت آپ کی باتوں کاجوہر تھی۔ ایک عرصہ سے دمہ کے عارضہ میں مبتلا تھے لیکن اس کے باوجود تہجد اوروظائف کی پابندی کرتے تھے۔
خاتمہ بھی ایسا اچھا ہواکہ خدا ہرمسلمان کونصیب کرے، خاص بقرعید کے دن عصرو مغرب کے درمیان جب کہ دنیائے اسلام میں ہرجگہ قربانیاں ہوئی ہوں گی، آپ نے اپنی جان ناتواں کی قربانی رب السماء والارض کی بارگاہِ کبریائی میں بڑی ہنسی خوشی کے ساتھ پیش کی اوررفیق اعلیٰ کاکلمہ پڑھتے ہوئے بڑے اطمینان وسکون کے...

موقع الكتاب في العملية النّقدية عند المحدّثين وأهمّ وسائل صيانته دراسة تأصيليّة

In this research paper the method invented by the critic scholars of hadeeth for the maintenance of quality. It is the sake of delivering the hadeeth to us the way it was narrated by the prophet peace be upon him. This study came to highlight the greatness of the critical approach of the Muḥaddithīn, this unique and precedent based approach has been opted and enjoyed the respect of the opponents. I have paid special regard to the timeline, which reflects the evolution of the Muḥaddithīn criticism, from the Era of the Prophet (PBUH) to the end of the Hadīth Narration Era. This paper shows the extent to which the critic scholars go in order to maintain the book; their attention is not limited to the Oral narration as claimed by the opponents of Sunnah and their stooges. This is done by examining the classified works of scholars that had preserved the bases and the rules followed in the criticism process, as explained in this study.

Molecular Genetic Analysis of Susceptible Diabetic Nephropathy Genes in Type 2 Diabetics

Diabetic Nephropathy (DN) is a major complication of both type 1 and type 2 diabetes and a leading cause of mortality due to End Stage Renal Disease (ESRD) worldwide. This overwhelming clinical problem is also affecting a number of diabetic patients in Pakistan. Several molecular pathways could lead to the development of DN. In this thesis, the role of genes in one classical pathway, the Renin Angiotensin Aldosterone System (RAAS) along with fatty acid metabolism, and cardiovascular related pathways were investigated in type 2 diabetics, nephropathy and ESRD cohorts. The aim was to see the allele and genotype frequency differences of Pakistani, French and UK population. The study is divided into three parts for Pakistani, French and UK cohorts. For Pakistani Punjabi population, 206 subjects mainly from the Faisalabad district were included. The study design comprised of four groups which were analyzed for biochemical and molecular characterization. PCR and PCR-RFLP based genotyping assays followed by Real Time PCR technique (TaqMan Assay) were carried out for the ACE, AGT, CYP11B2 and ACACB genes to identify the genotypes of each group individually, and calculate and compare their genotype frequencies among four groups as well with individual non-genetic parameters in each group. The association of genotypes was analyzed for their correlation with all of the biochemical parameters, as well as with hypertension, family history of diabetes and nephropathy status. The results showed the association of CYP11B2 gene polymorphism (T/C) with diabetes with OR (95%CI, P value) of 3.20 (1.15-8.91, 0.02), and a significant association of ACACB gene polymorphism (G/A) with obesity/BMI (P =0.009) and type 2 diabetes (P=0.02). For French cohorts, one of the genes of fatty acid metabolism pathway i.e. ACACB (G/A) was analyzed in five different cohorts (n=7438) of diabetic patients who were at various stages of nephropathy. The genotypes were compared for ethnic variations as well as association for different parameters. Results showed a significant association (P=0.02) with ESRD. For UK population, the association study of cardiovascular and hypertension related SNPs in LPA, DAB2IP and TLL1 genes with baseline characteristics or disease outcomes in four UK cohorts (n=5602) was performed. Results showed LPA SNPs association with serum Lp(a) levels in one of the cohorts (NPHS-II group), whereas for DAB2IP SNP (rs7025486), the significant association with High Density Lipoprotein levels (P=0.01) and Diastolic Blood Pressure (P=0.03) was observed. From this study, it is suggested that if similar studies are carried out on large number of samples (replication and meta-analysis), it will be helpful in identifying genetic biomarkers for DN on the basis of ethnic variations and devising pharmacogenomics based interventions.
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